Advancing Protein Manufacturing

Roke’s technology platform combines two-stage fermentation with advanced tools to develop low-cost scalable protein manufacturing processes.

Streamlined Process Development

Two-stage fermentation decouples cell growth from protein expression, enabling the use of high-performing standard scalable processes across multiple proteins of interest. This approach accelerates process development without sacrificing performance.

Low Cost Protein Purification

We program purification steps directly into our strains, effectively reducing the number of steps in the purification process. This simplification leads to lower manufacturing costs and capital expenses, as well as a faster overall process.

Unlocking New Possibilities

Roke’s technology unlocks previously inaccessible markets and applications for proteins by operating beyond traditional growth-associated boundary conditions. We leverage advanced tools to create novel strains that express hard-to-make proteins at unprecedented levels.